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RD items of Total 12% 8% to 12% 4% to 8% 3% to 4% 2% to 3% 1% to 2% 0.5% to 1% 0.5% Number of PCTS in year to September 2007 Projected number of PCTs in March 2008 It was expected that Repeat Dispensing would be best suited to patients with chronic conditions that are considered likely to remain stable for the duration of the repeatable prescription. It is no surprise then that the majority of items prescribed under repeat dispensing in the year to September 2007 are lipid regulating drugs cholesterol ; and ReninAngiotensin System Drugs hypertension.
QUETIAPINE Seroquep ; A 35 yr old man seen in the ED three weeks earlier for a suicide attempt, was found in cardiac arrest following a suspected overdose of quetiapine. The autopsy showed evidence of aspiration of gastric contents. Blood quetiapine level: 13, 960 ng ml AAPCC 2001 #798 ; Depressed sensorium Hypotension tachycardia * QT interval prolongation A 15 yr old F presented to the ED claiming to have ingested 2 quetiapine tablets. HR 150 decreased to 115 during her ED stay. No ECG was obtained Transferred to psychiatry unit. Six hrs later she was transferred back to the ED with fixed and dilated pupils with seizures. CPR was unsuccessful. AAPCC 2006 #1052.
ORDER This case is currently before the court on the parties' cross motions for summary judgment. The court heard oral arguments on May 6, 2008. For the reasons stated in the accompanying Memorandum Opinion, it is hereby ADJUDGED AND ORDERED that the case be REVERSED and REMANDED pursuant to sentence four of 42 U.S.C. 405 g ; for further administrative review consistent with the Memorandum Opinion. The Clerk of Court is directed to send copies of this Order and the accompanying Memorandum Opinion to all counsel of record. Enter this 2nd day of July, 2008.
Amisulpride Solian ; , Sedation, which can make it difficult for people to get up in the morning. Aripiprazole Abilify ; , Clozapine Weight gain this varies depending on which drug you are taking; it seems to be more of a problem with clozapine and olanzapine. Clozaril ; , Olanzapine Zyprexa ; , Metabolic syndrome: a number of these drugs seem to cause some problems with blood glucose levels resulting in a person developing type II diabetes, Quetiapine Seroque ; , although this is complicated by the fact that people with schizophrenia are more likely to become diabetic. The medication can also cause hyperlipidaemia the Risperidone Risperidal ; , Zotepine presence of too much fat circulating in the blood ; . Zoleptil ; The atypical antipsychotics are less likely to produce the extrapyramidal side effects and hormonal side effects described above for the typical antipsychotics although it does depend on the drug.
A randomised controlled trial in 52 australian aged-care facilities3 demonstrated that providing an education program for staff in combination with pharmacist-conducted medication review reduced medicines use without affecting patient survival, hospitalisations, or quality of life: reduced overall administration of drugs to residents 24% fewer antipsychotic agents 21% fewer sedative hypnotics a trend toward longer survival in residents of facilities where the intervention was applied the intervention was found to be cost-effective.
In 1995, the Institute of Medicine IOM ; produced a study titled Federal Regulation of Methadone Treatment Institute of Medicine 1995 ; . This study concluded that FDA regulations were inhibiting physicians For more than from exercising their professional judgthree decades, ment; isolating methadone treatmethadones use to ment from mainstream medicine, treat addiction has thereby depriving patients of important been subjected to ancillary services; and discouraging extensive Federal, research into new medications. This IOM study recomState, and local mended that the Federal regulation. regulatory process be modified to and sarafem.
Among people with a 5-year cardiovascular risk 15%, the aim of treatment is to lower cardiovascular risk to 15% see table 11.
Present state of knowledge concerning pathogenesis, diagnosis, treatment and prevention of venous and arterial thrombosis is concisely reviewed by experts in the field. In-depth coverage is given to mechanisms and factors involved in the pathogenesis of venous thrombosis; the current concept of the hypercoagulable state ; recent advances in the development of noninvasive methods for the diagnosis of venous thrombosis which have demonstrated the inaccuracy of the clinical diagnosis of deep vein thrombosis; the role of ventilation perfusion scanning and pulmonary angiography in the diagnosis of thromboembolism; the efficacy of low dose heparin therapy and external pneumatic calf compression in the prevention of venous thrombosis with particular reference to the surgical patient ; practical aspects of anticoagulant therapy ; the role of platelets, vascular injury and prostaglandin synthesis in the vessel wall and platelets, and risk of and progression of premature atherosclerosis; the role of thrombosis and anti-thrombotic agents in myocardial infarction, cerebrovascular occlusive disease, and gbmerular renal disease; and the clinical efficacy of antiplatelet drug therapy in both atherovascular disease and venous thromboembolism and sinequan.
Our pipeline includes the life-cycle management initiatives for approved products mentioned above, as well as development compounds across the whole discovery and development cycle. Our product pipeline and life-cycle management efforts are focused on the important areas of psychiatry, analgesia, neurology and anaesthesia. Following the disease area review described on page 38 we took the decision to discontinue discovery work in Parkinson's disease, multiple sclerosis and neuroprotection in stroke, but current projects in development will continue as planned. Psychiatry In psychiatry, we continue to expand the opportunities for Seroquel. Clinical programmes for GAD and MDD using the Seeoquel SR formulation are underway. An additional clinical programme with S3roquel SR was initiated in bipolar disorder in December. Filings for all these programmes are anticipated in 2008. To strengthen our psychiatry pipeline in 2006, we progressed two compounds, AZD2327 and AZD3783, into clinical development for the treatment of anxiety and depression. Analgesia In pain control, our research focus is nociceptive pain caused by tissue damage ; and neuropathic pain caused by nerve damage ; . We will expand our research capabilities in the area of chronic pain by building on the phage and ribosome technologies owned by Cambridge Antibody Technology Group plc. Our three candidate drugs in development from the collaboration we entered into with NPS Pharmaceuticals, Inc. in March 2001, have been joined by AZD1940 and AZD1386 potential analgesics from our Montreal discovery laboratories. In August, we announced an exclusive global agreement with Pozen Inc. to co-develop fixed-dose combinations utilising Pozen's proprietary formulation technology. The initial development is PN-400, a fixed-dose combination of naproxen and esomeprazole, which has the potential to provide chronic pain sufferers with a new treatment that has good efficacy and a low upper gastrointestinal side-effect profile.
TREATMENTS FOR METABOLIC DISORDERS Cardiac- amlodipine Norvasc ; , aspirin all formulations, all generics ; , atenolol Tenormin, all generics ; , carvedilol Coreg ; , clonidine Catapres, all formulations, all generics ; , digoxin all manufacturers ; , dilitiazem Cardizem, CD, SR, Cardia XT, Tiazac ; , enalapril Vasotec, all generics ; , furosemide Lasix, generics ; , hydrochlorothiazide generics ; , levothyroxine Synthroid, Levothyroid, Levoxyl, generics ; , lisinopril Prinivil, Zestril, all generics ; , metolazone Mykrox, Zarosolyn, all generics ; , metoprolol Lopressor, Toprol SL, all formulations, all generics ; , nifedipine Adalat, CC, Procardia, XL, all generics ; , propranolol Inderal, all generics ; , spironolactone Aldactone, all generics ; , triameterene Dyrenium, generics, all comibinations ; , valsartan Diovan ; , verapamil Calan, SR, Covera, Isoptin, Verelan, generics ; . Diabetic- acarbose Precose ; , clorpropamide Diabinese ; , glimepiride Amaryl ; , glipizide Glucotrol ; , glyburide Diabeta, Micronase ; , insulin all types ; , metformin Glucophage ; , pioglitazone Actos ; , rosiglitazone Avandia ; , tolazamide Tolinase ; , tolbutamide Orinase ; . Hyperlipidemia- atorvastatin Lipitor ; , cholestyramine Questran ; , colesevelam Welchol ; , ezetimibe Zetia ; , fenofibrate Tricor ; , gemfibrozil Lopid ; , niacin Niaspan, Nicotinic Acid, Slo-Niacin ; , pravastatin Pravachol ; , rosuvastatin Crestor ; . Wasting- carafate Sucralfate ; , cyproheptadine Periactin ; , diphen-atopine Lomotil ; , dronabinol Marinol ; , esomeprazole Nexium ; , famotidine Pepcid ; , lansoprazole Prevacid ; , megestrol acetate Megace ; , omerprazole Prilosec ; , pancrease Enzymes all formulations, generics ; , pantoprazole Protonix ; , rabeprazole Aciphex ; , ranitidine Zantac ; , testosterone replacement products All types ; . ALL OTHERS albuterol inhaler Ventolin ; , albuterol ipratropium Combivent ; , alprazolam Xanax ; , amitriptyline Elavil ; , amoxapine Asendin ; , azelastine Astelin ; , beclomethasone Beclovent, Vanceril, Qvar ; , brompheniramine Dimetapp, various ; , budesonide Pulmicort ; , busipirone Buspar ; , buproprion Zyban, Wellbutrin ; , carbamazepine Tegretol ; , cetirizine Zyrtec ; , chlordiazepoxide Librium ; , citalopram Celexa ; , clemastine Tavist ; , clomipramine Anafranil ; , clorazepate Tranxene ; , codine pain relievers, desipramine Norpramin ; , desloratadine Clarinex ; , dexamethasone all forms ; , dexchlorpheniramine Polaramine, various ; , diazepam Valium ; , diclofenac Cataflam, Voltaren, generics ; , diphenhydramine Benadryl ; , docusate-sennoside Senokot S ; , dulozetine Cymbalta ; , estazolam Prosom ; , ethosuximide Zaronton ; , etodolac Lodine, generics ; , fenoprofen Nalfon, generics ; , fentanyl Transdermal Duragesic ; , ferrous sulfate Feosol, Mol-Iron, Slow Fe ; , fexofenadine Allegra ; , flunisolide Aerobid ; , fluoxetine Prozac ; , flurazepam Dalmane ; , flurbiprofen Ansaid, generics ; , fluticasone Flovent ; , fluticasone salmeterol Advair Disdus ; , fluvoxamine Luvox ; , gabapentin Neurontin ; , hemorrhoidal creams & suppository, hepatitis A, B vaccine Havrix, Vaqta, Energix-B, Recombivax HB, Comvax, Twinrix ; , hydrocodone and derivatives, hydroxyzine Vistaril, generics ; , ibuprofen Motrin ; , imipramine Tofranil ; , ipratropium Atrovent ; , isoproterenol Isuprel ; , ketoprofen Orudis, generics ; , klonopin Clonazepam ; , lamotrigine Lamictal ; , lebetalol trandate, normodyne ; , levetiracetam Keppra ; , lexapro Escitalopram ; , lithium Eskalith, Lithobid ; , loperamide HCL Imodium ; , lorazepam Ativan ; , loratadine Claritin ; , maprotiline Ludiomil ; , meclofenamate generics ; , meloxicam Mobic ; , meperidine Demerol, generics ; , metaproterenol Alupent ; , minoxidil Loniten ; , mirtazapine Rameron ; , montelukast Singulair ; , morphine MSIR, Oramorph SR, MS Contin ; , naproxen Aleve, Anaprox, Naprosyn, Anprelan ; , nabumetone Relafen ; , nefazodone Serzone ; , nembutal Pentobarbital ; , nicotene replacement products - all forms, nizatidine Axid ; , nortriptyline Aventyl, Pamelor ; , nystatin triamcinolone cream, olanzapine Zyprexa ; , oxaprozin Daypro ; , oxazepam Serax ; , oxycodone Endocodone, Oxycontin, Roxicodone, OxyIR, OxyFAST, M-oxy ; , paroxetine HCL Paxil ; , peg-interferon alfa-2b & ribavirin Peg-Intron Rebetol ; * , peg-interferon alfa-2a & ribavirin Pegasys Copegus ; , * phenytoin Dilantin ; , prochloparazine Compazine ; , promethazine Phenergan, generics ; , propoxyphene Darvon ; , protriptyline Vivactil ; , quetiapine Ser9quel ; , ribiavirin and interferon Rebetron ; * , salmeterol Serevent ; , sertraline Zoloft ; , sulindac Clinoril ; , temazepam Restoril ; . terbutaline Brethine, Brethaire ; , tiagabine Gabitril ; , tolmentin Tolectin ; , triazolam Halcion ; , triamcinolone Azmacort ; , trimipramine Surmontil ; , valproic Acid Depakote, Depakene ; , venlaxifine HCL Effexor ; , zolpidem Ambien ; . Removed in 2005 - celecoxib Celebrex ; , rofecoxib Vioxx ; , valdecoxib Bextra and buspar.
In industrialized countries, viruses are the predominant cause of acute diarrhea and show distinct winter seasonality. Rotavirus. Leading cause of severe, dehydrating gastroenteritis among children. One-third of diarrhea hospitalizations and 500 000 deaths worldwide each year.
Flexible lessons often with timetables to fit local needs. These Access centres are managed by local communities and act as `feeder' schools linked to the nearest primary school. District and provincial governments have been involved in planning, running and assessing ActionAid's Access programme, so it can continue when ActionAid's involvement comes to an end and atarax.
Conclusion The use of BioEpisteme to predict mechanisms of action for very large molecular libraries is a good example of how to find potential new uses for known compounds. The experimental validation of the predicted results can be a starting point for a repurposing project. The development of existing drugs for new indications allows researchers to take advantage of all the information already known about a compound.
To investigate the nature of the C. Sordellii bacteria, the FDA and CDC held the "Emerging Clostridial Disease" workshop on May 11, 2006. 151 Workshop presenters experts in the fields of pharmacology, immunology, and maternal-fetal medicine noted that the rapid growth of the C. Sordellii bacteria likely forecloses effective treatment; 152 that there is no currently identifiable "window of opportunity" for treatment once a woman is infected, even with major interventions such as hysterectomy; 153 and that antibiotic prophylaxis was unlikely to provide any protection in the RU-486 C. Sordellii context. 154 The fatality rate has been 100% for the women who contracted C. Sordellii infection after RU-486. In an effort to dismiss any association between RU-486 and the C. Sordellii deaths, some have promoted the idea that C. Sordellii is linked to pregnancy and childbirth, not the abortion pill. However, in five years, five women have died from this infection after taking RU-486. In contrast, the FDA has noted that there were "only five additional cases not associated with and pamelor.
While US-based producers of APIs are inspected by the FDA to assure GMP compliance, APIs made abroad may escape profound inspection and the accompanying scrutiny of their quality control systems. Many EU-based API manufacturers have been inspected by the US FDA and in some EU Member States also by their national authorities. However, in many other parts of the world where API inspection and enforcement has been largely absent, there is no incentive for manufacturers to incur the significant extra costs necessary to meet cGMPs. The problem seems even more serious than "mere" non-compliance with GMP; it appears that even companies in China and India that have been blacklisted by Nigeria's health authorities NAFDAC 16 because of their proven, deep involvement in exporting counterfeit medicines to that country, are still freely exporting APIs to the EU. Thus the health of our citizens is put at risk from sub-standard medicines. FDA has this year issued Warning Letters to some of the leading firms in India. 17 Is this the tip of the iceberg? Are fast growth and compliance difficult to reconcile? Whatever the answer, increased patient risk should never be a consequence of financial success.
Europe-wide programme designed to promote international experience sharing and transfer of know-how. The Vitamins and Fine Chemicals Division has revamped its management development and succession planning, with the main focus on preparing successors for key posts. September 2000 saw the ground-breaking ceremony for Roche's new international training and conference centre for senior managers, Roche Forum Buonas, which is being established on the scenic Buonas Peninsula, Lake Zug, Switzerland. The new complex will incorporate a conference area, meeting rooms, a restaurant and an accommodation wing. If the ambitious timetable is met, we expect the centre to be operational early in 2002 and glyset.
I was on seroquel a few months back for my anxiety, but after a week and a half it gave me the shakes and oculogyric crisis where you cant control your eye movements ; , but not everyone gets that though, and it did help with sleeping a whole lot.
Whereas people often make reference to the fascinating or alluring aspects of gambling as an explanation to account for gambling, it should be appreciated that similar notions may be invoked in reference to many other things that people find intriguing. Instead of stopping there, thus, the more consequential issues pertain to how people develop and sustain fascinations with anything -- whereby matters such as gambling, drinking, music, sports, religion or love connote but variants of the more general human capacity for developing and maintaining intrigues with things. As with the other aspects of activity considered here, the matter of people developing fascinations with things considered disreputable or troublesome is given more extended attention in Prus and Grills 2003 ; , but Henry Lesieur's The Chase provides some particularly valuable insight into the way in which people develop and sustain fascinations with racetrack gambling. As is quickly evident in Lesieur's study, people's fascinations seldom develop around the aesthetics of the race or the beauty, grace and strength of well-bred horses in motion. Newcomers may attend to such things and both trainers and more experienced gamblers are apt to be highly concerned about the condition of particular horses and the track. Still, for more experienced gamblers, the emphasis more fully revolves around the matters of accessing money, defining probabilities, finding modes of hedging bets and achieving winning numbers. Thus, without denying aspects of the situation that participants may find enjoyable in various ways, it is important to recognize the ways in which gamblers also "work at, " struggle with and become frustrated with their activities. Whereas some may have been attracted to the prospects of "quick and and precose.
6. Can you give me written directions on how to take SEROQUEL XR? What should I do if miss a dose?.
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America's coastlines provide outstanding tourism and recreation opportunities, as well as crucial wildlife habitat for a host of coastal and marine species. A moratorium on offshore oil and gas drilling has protected the bulk of our sensitive coastlines for almost two decades.The ban has been renewed year after year due to the support of an overwhelming majority of citizens in coastal states, who oppose the adverse effects that offshore development will have on critical shoreline habitat and regional economies that depend largely on tourism. The Bush energy plan threatens to undo this protection for some coastal areas, threatening our shorelines and rich coastal waters with devastating oil spills as well as the routine but substantial pollution associated with oil and gas development and torsemide.
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Please note that FASLODEX fulvestrant injection ; , ZOLADEX goserelin acetate implant ; , and SEROQUEL quetiapine fumarate ; will be shipped to the physician's office. All other products will be shipped to the patient's address, unless otherwise specified. Medication will be sent in a 90-day supply; therefore, prescriptions should reflect a 90 day supply of medication for each product. Exceptions to this 90-day supply are as follows: PULMICORT RESPULES budesonide inhalation suspension ; must indicate whether the product is to be administered once or twice daily and may be written for a 30-day, 60-day, or 90-day supply.
Line drawing represents the possible abnormalities of the low-set, deformed, or absent ears; wide-set eyes; depressed bridge of nose; enlarged head; and small chin and glucophage and Order seroquel.
1. The list of adverse reactions of current concern is on page 26. 2. The list of medicines in the Intensive Medicines Monitoring Programme IMMP ; is on page 27.
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In these studies, the most commonly observed adverse events associated with the use of seroquel incidence of 5% or greater ; and observed at a rate on seroquel at least twice that of placebo were somnolence 18% ; , dizziness 11% ; , dry mouth 9% ; , constipation 8% ; , sgpt increased 5% ; , weight gain 5% ; , and dyspepsia 5 and actoplus.
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Fellow Correspondent: Molly C. Carr, MD Acting Instructor Senior Research Fellow Division of Metabolism, Endocrinology, and Nutrition University of Washington Seattle, WA Presenters: Oluf Pedersen, MD Professor of Diabetology Steno Diabetes Center Copenhagen, Denmark Amanda Adler, MD, PhD Oxford University Diabetes Trials Unit Radcliffe Infirmary Oxford, United Kingdom.
In some patients the need for therapy continues until adult age, in others the therapy can be discontinued as symptoms are alleviated and new skills learned. Studies have shown that the therapy continues for more than two years in on average a third of the patients. When discontinuation is considered in a balanced situation, an interval with no medication may for example be introduced, and the extent of the symptoms and disability experienced by the patient at home, in school and in other situations based on questionnaires and clinical reviews ; are assessed. Medical therapy can be discontinued when the symptoms no longer constitute a significant disability. The continuation of other forms of treatment is generally advised. In the planning of medical therapy any possible risks should also always be considered: there should be awareness of their existence, and their significance should be compared with the benefits of the medical therapy. Treatment of ADHD offers clear evidence of benefits, and in addition to the decrease in the actual symptoms, reduced abuse and reduced risk of accidents can for example be distinguished. The current treatment recommendations are there to assist the clinician in the planning and carrying out of the overall treatments. New forms of drugs are being developed and introduced. The possibility of abuse is reduced as drugs which the FDA has already approved such as the methylphenidate transdermal system MTS ; and lisdexamfetamine, which is a precursor of dextroamphetamine and bio-degradable in the intestines, are introduced on to the market.
AstraZeneca is a financial contributor to the National Packaging Covenant and committed to the principles of the Covenant. The challenge for AstraZeneca is to identify ways of reducing packaging, whilst still ensuring the efficacy of the medicines we produce. AstraZeneca operates in Australia as a pharmaceutical manufacturer, formulating and packaging a broad range of pharmaceuticals for Australian and world markets. As a packaging user within the packaging supply chain AZA has applied the focus of the action plan to AZA Supply and Manufacturing Division. The Action Plan covers a 3-year period 2007- 2010 ; . Data and progress toward targets will be reported in the annual report. The Action Plan demonstrates the commitment of AstraZeneca Australia to progressively reducing the environmental impact of the consumer packaging throughout the product lifecycle. 2. AstraZeneca Australia AZA ; Overview AstraZeneca Australia is the Australian subsidiary of the global pharmaceutical company AstraZeneca PLC. Established in Australia in 1957 AZA celebrated its 50year anniversary in 2007. AstraZeneca has expanded to a company that employs more than 900 people with an annual turnover of billion. Our broad product portfolio includes many world leaders and a range of high potential therapies for treating cancer, gastrointestinal disease, asthma, hypertension, lowering lipids, general and local anesthetic, migraine as well as schizophrenia. Leading products on the Australian market include: Arimidex, Faslodex, Casodex, and Zoladex for cancer Nexium for reflux and ulcers; Symbicort, Pulmicort and Oxis for asthma Zestril, Plendil, Tenormin, Betaloc and Atacand for high blood pressure; Crestor for lowering lipids; Diprivan, the general anaesthetic; Xylocaine and Naropin, local anaesthetics; Zomig for treating migraine; and Seroquel for treating schizophrenia.
| Discount DrugsWhy are we learning about TB? TB is highly contagious. TB is deadly. TB can be cured. TB is a major killer of people with HIV.
1-123 Seroquel oral dose TIPS Question: What is the maximum dose per day of Seroquel recommended for the elderly? This medication is usually prescribed BID. Would it be beneficial to have it prescribed TID considering the elimination of half-life of 6-7 hours. Response: Seroquel: As you are aware, Seroquel is one of the so-called newer atypicals. Experience with this medication in clinical practice is in comparison to the traditional and other atypicals, early and ongoing and definitive norms in terms of dosage range are still being established. In recent clinical studies however, average doses have been in the order of 125-150 mg. However a wide range is often used, reflecting the individuality of older persons. Sometimes doses up to 400 to 500 mgm, if tolerated, can be used. The adage start low, go slow and monitor closely for benefits and side effects" using your behavioural instruments, your DOS, your Cohen Mansfield, the 7 clinical parameters, are going to be critical in regards to helping us as a field as well as for individual purposes to find the appropriate doses for each patient. At present, a bid dosage is my usual practice. As you recall, you can remember side effects of the atypicals by remembering the acronym DASH watch for Dizziness, Akathesia, Somnolence and Hypotension and buy sarafem.
Reference List 1. Hermanek P. pTNM and residual tumor classifications: problems of assessment and prognostic significance. World J Surg 1995; 19: 184-90. Greene, F. L. Page D. L. Fleming I. D. et al. American Joint Committee on Cancer - Cancer staging handbook, TNM classification of malignant tumors. 129. 2002. New York: Springer. 3. Joseph NE et al. Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. Ann Surg Oncol 2003; 10: 213-8. Wittekind C. TNM Klassification maligner Tumoren. Meyer HJ, Bootz F. 2002. Springer, Berlin. Greenson JK et al. Identification of occult micrometastases in pericolic lymph nodes of Duke's B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49. Correlation with long-term survival. Cancer 1994; 73: 563-9. Liefers GJ et al. Micrometastases and survival in stage II colorectal cancer. N Engl J Med 1998; 339: 223-8. Cabanas RM. An approach for the treatment of penile carcinoma. Cancer 1977; 39: 456-66. Giuliano AE, Jones RC, Brennan M, Statman R. Sentinel lymphadenectomy in breast cancer. J Clin Oncol 1997; 15: 2345-50. Morton DL et al. Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg 1992; 127: 392-9. Bilchik AJ et al. Ultrastaging of early colon cancer using lymphatic mapping and molecular analysis. Eur J Cancer 2002; 38: 977-85. Bilchik AJ et al. Effect of lymphatic mapping on the new tumor-node-metastasis classification for colorectal cancer. J Clin Oncol 2003; 21: 668-72. Paramo JC et al. Intraoperative sentinel lymph node mapping in patients with colon cancer. J Surg 2001; 182: 40-3. Paramo JC, Summerall J, Poppiti R, Mesko TW. Validation of sentinel node mapping in patients with colon cancer. Ann Surg Oncol 2002; 9: 550-4. Saha S, Nora D, Wong JH, Weise D. Sentinel lymph node mapping in colorectal cancer--a review. Surg Clin North 2000; 80: 1811-9. Saha S et al. Technical details of sentinel lymph node mapping in colorectal cancer and its impact on staging. Ann Surg Oncol 2000; 7: 120-4. Saha S et al. Ultrastaging of colorectal cancer by sentinel lymph node mapping technique--a multicenter trial. Ann Surg Oncol 2001; 8: 94S-8S. Saha S. Selective lymph node mapping in colorectal cancer--a prospective study for impact on staging, limitations and pitfalls. Cancer Treat Res 2002; 111: 109-16.
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